间歇性禁食有利于调节adipokines,并可能减轻动脉样硬化
Mohammad Al Zein1, Omar Zein2, Rawan Diab2
1Faculty of Medical Sciences, Lebanese University, Hadath, Beirut, Lebanon.
Biochemical pharmacology
|October 23, 2023
概括
间歇性禁食 (IF) 可以通过改善阿迪波金平衡和减少炎症来帮助管理与肥胖相关的动脉样硬化. 本综述探讨了IF如何影响adipokines和动脉样硬化,提供了潜在的饮食干预.
科学领域:
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
- 营养科学 营养科学
背景情况:
- 脂肪组织作为内分泌器官起作用,分泌调节生理过程的脂肪素.
- 阿迪波金失调与肥胖和心脏代谢疾病风险增加有关,包括动脉样硬化.
- 动脉样硬化是心血管死亡的主要原因,受阿迪波金失衡的影响.
研究的目的:
- 审查adipokines在动脉样硬化病原发生中的作用.
- 讨论间歇性禁食 (IF) 作为肥胖相关动脉样硬化症的管理策略.
- 探索IF对动脉样硬化相关的炎症标志物的有益影响.
主要方法:
- 对adipokines,肥胖,动脉样硬化和间歇性禁食的研究进行文献综述.
- 分析IF对阿迪波金分泌和炎症通路的影响.
- 综合证据证明IF与改善心脏代谢健康和降低动脉样硬化风险有关.
主要成果:
- 阿迪波金在动脉样硬化的发展和进展中起着至关重要的作用.
- 间歇性禁食显示出显著的抗炎作用,并促进体重减轻.
- IF积极调节阿迪波金 (adipokine) 配置文件,减轻心脏代谢综合征的关键方面.
结论:
- 阿迪波金不平衡是导致肥胖相关动脉样硬化的重要因素.
- 间歇性禁食显示出作为一种有效的饮食干预措施来管理与肥胖相关的动脉样硬化.
- 伊弗的减少炎症和改善代谢标记的能力支持其在动脉样硬化预防中的潜在作用.
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