参与者与协议研究的经验 在脏精密医学项目中的脏活检
Angela M Victoria-Castro1, Celia P Corona-Villalobos2, Alan Y Xu2
1Clinical and Translational Research Accelerator, Yale School of Medicine, New Haven, Connecticut.
Clinical journal of the American Society of Nephrology : CJASN
|October 23, 2023
概括
精密医学项目 (KPMP) 研究活检的参与者主要是以利他主义为动机. 大多数参与者理解知情同意过程,并发现这项研究具有影响力.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 临床研究 临床研究
- 患者体验 患者体验
背景情况:
- 脏活检在病学和研究中至关重要.
- 脏精密医学项目 (KPMP) 使用研究脏活检.
- 评估参与者在KPMP中的经验至关重要.
研究的目的:
- 评估参与者在KPMP中接受研究脏活检的经验.
- 了解参与者的动机,理解和结果.
主要方法:
- 在KPMP中,有111名患有AKI或CKD的参与者完成了活检后调查.
- 该调查评估了动机,知情同意,疼痛,焦虑,满意度和对生活的影响.
- 从2019年9月到2023年1月,在美国9个地点收集的数据.
主要成果:
- 利他主义是59%的参与者的首要动机.
- 99%的人理解知情同意,而97%的人承认他们的研究作用.
- 50%的人在活检期间报告疼痛 (中位数1/10) 和64%的焦虑 (中位数3/10).
- 超过一半的人报告了对饮食,活动和对脏疾病的看法的影响.
结论:
- 在很大程度上,KPMP参与者的动机是帮助他人的愿望.
- 参与者对KPMP中的知情同意过程有很好的理解.
- 在KPMP中研究脏活检对参与者的生活产生了显著的影响.
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