烧伤中的阿片类药物处方和阿片类药物障碍:从1990年到2019年的大型数据库分析
Elvia Villarreal1, Steven E Wolf2, George Golovko3
1School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Burns : journal of the International Society for Burn Injuries
|October 23, 2023
概括
在烧伤患者中,阿片类药物的使用发生了转变,氧化变得越来越常见. 自2000年以来,阿片类药物相关疾病的风险几乎翻了一番,需要谨慎的疼痛管理策略.
科学领域:
- 疼痛管理 疼痛管理
- 烧伤护理 烧伤护理
- 公共卫生 公共卫生
背景情况:
- 阿片类药物对于治疗严重烧伤疼痛至关重要.
- 缺乏对阿片类药物使用模式和烧伤患者相关并发症的详细分析.
研究的目的:
- 分析过去三十年来阿片类药物处方的趋势以及烧伤患者中阿片类药物相关并发症的发生率.
- 从1990年到2019年,确定阿片类药物处方模式和相关风险的变化.
主要方法:
- 使用了TrinetX的无身份患者数据库.
- 包括在内的患者在1990年至2019年期间处方阿片类药物后烧伤伤.
- 按十年进行分层分析 (1990-1999,2000-2009,2010-2019) 以评估与阿片类药物相关的疾病,依赖,滥用,故意自伤以及精神/行为障碍.
主要成果:
- 可在20世纪90年代和2000年代流行;氧可在2010年代导致处方.
- 20世纪90年代与2000年代相比,阿片类药物相关疾病,依赖,滥用和自我伤害的风险有所降低.
- 将2000-2009年与2010-2019年进行比较,发现与阿片类药物相关的疾病,依赖,滥用和故意自伤的风险显著增加.
结论:
- 自2000年以来,烧伤患者中阿片类药物相关疾病的发生率几乎翻了一番.
- 提高警和谨慎的处方做法对于烧伤患者的疼痛管理至关重要.
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