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Updated: Jul 12, 2025

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使用多omics方法对Helicobacter pylori氧化还原开关HP1021 regulon进行分析

Mateusz Noszka1, Agnieszka Strzałka2, Jakub Muraszko1

  • 1Department of Microbiology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.

Nature communications
|October 23, 2023
PubMed
概括

氧化还原开关蛋白HP1021调节Helicobacter pylori对氧化应激的反应,控制基因表达和蛋白质水平. 这种蛋白质是管理活性氧物种 (ROS) 和维持细胞能量平衡的关键.

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Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
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