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Updated: Jul 12, 2025

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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通过Bre1进行的素H2B单双化机制

Fan Zhao1, Chad W Hicks1, Cynthia Wolberger2

  • 1Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Nature structural & molecular biology
|October 23, 2023
PubMed
概括

基斯H2B的无处不在性调节了关键的细胞过程. Bre1 E3 酶结构显示了它如何结合核细胞和DNA,指导无胺转移,并表明了基因素 E3 酶特异性的一般机制.

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