随着有氧运动,计算机认知训练和它们的组合在身体不活跃的健康中年后的成年人身上,内在的功能性大脑连接性发生了变化:Projecte运动
Stavros I Dimitriadis1,2, Alba Castells-Sánchez3,4, Francesca Roig-Coll3,4
1Department of Clinical Psychology and Psychobiology, University of Barcelona, Passeig Vall d'Hebron 171, 08035, Barcelona, Spain. stidimitriadis@gmail.com.
GeroScience
|October 23, 2023
概括
结合有氧运动和认知训练,改善了老年人的大脑连接. 生活方式干预措施在老年人群中对神经保护和认知增强具有临床意义.
科学领域:
- 神经科学是一个神经科学.
- 衰老研究研究 衰老研究
- 认知科学 认知科学
背景情况:
- 生活方式干预表明在衰老中具有神经保护作用.
- 关联休息状态功能连接 (rsFC) 变化与认知改善的确切机制仍在研究中.
研究的目的:
- 研究有氧运动 (AE),计算机认知训练 (CCT) 和它们的组合 (COMB) 对rsFC和认知功能的影响.
- 探索RSFC的变化如何调解认知效益.
主要方法:
- 一项为期12周的随机对照试验 (Projecte Movement) 涉及82名参与者 (平均年龄58.38±5.47岁).
- 多模式数据采集协议,以评估rsFC和认知表现.
- 干预组的高坚持率 (>80%) 在干预组.
主要成果:
- 在COMB组中,前后默认模式网络 (aDMN/pDMN) 内部和之间出现了改变的rsFC,在补充运动区域和右丘脑之间出现了减少的rsFC.
- 在AE和COMB组中没有观察到显著的全球或本地rsFC变化介导的认知益处.
结论:
- 生活方式干预,特别是综合方法,对衰老具有临床意义.
- 这项研究提供了结合有氧运动和认知训练对神经保护和认知增强的潜在益处的证据.
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