对于杜普伊特伦病的原酶注射后的延迟血管并发症
Jesper Nordenskjöld1,2, Jonas Nilsson3, Roua Kalaf3
1Department of Orthopedics, Hässleholm- Kristianstad Hospitals, Hässleholm, Sweden. jesper.nordenskjold@skane.se.
BMC musculoskeletal disorders
|October 23, 2023
概括
对于杜普伊特伦病的原酶注射后的延迟血管并发症是罕见的,但有可能发生. 外科医生和患者应该意识到这种风险,特别是在治疗小指时.
科学领域:
- 整形外科手术 整形外科手术
- 手部手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手 ...
- 药理干预措施 药理干预措施
背景情况:
- 大规模的试验和系统性审查报告,在杜普伊特伦病的原酶注射后没有血管不良事件.
- 这项研究呈现了一系列在原酶治疗后延迟血管并发症的病例.
研究的目的:
- 报告Dupuytren疾病的原酶治疗后延迟血管并发症的病例系列.
- 提高人们对与原酶注射相关的潜在罕见血管风险的认识.
主要方法:
- 对1181名接受原酶治疗的患者的前性评估.
- 详细收集患者的人口统计数据,症状和身体检查结果.
- 使用了冷不耐受症症状严重程度 (CISS) 尺度和数字动脉的多普勒声学.
主要成果:
- 三名患者在治疗数月后报告了延迟的血管并发症症状.
- 症状包括偶尔出现的白色变色,疼痛,麻醉,硬和虚弱,通常是由暴露于寒冷引起的.
- 多普勒超声波显示,在一个病人身上有一个非专利的腹数字动脉.
结论:
- 在杜普伊特伦病的原酶治疗后,延迟的血管并发症是罕见的.
- 对于外科医生和患者来说,意识到这种潜在风险至关重要,特别是在治疗小指时.
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