在移植后移植功能的那不勒斯预后得分:回顾性分析
İsmail Aytaç1, Betül Güven Aytaç1, Oya Kilci1
1Department of Anesthesiology, Ankara City Hospital, Ankara, Turkey.
Annals of transplantation
|October 24, 2023
概括
一个高的那不勒斯预后得分,反映了炎症和营养不良,与移植后功能下降有关. 这一分数可以预测移植患者的较低的肌素减少比率和潜在的移植功能障碍.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 免疫学 免疫学 免疫学
背景情况:
- 那不勒斯预后评分通过使用白蛋白,总胆固醇,中性细胞/淋巴细胞比率 (NLR) 和淋巴细胞/单细胞比率 (LMR) 来评估炎症和营养状况.
- 手术前的炎症和营养状况可以影响移植后的移植功能.
研究的目的:
- 根据术后肌氨酸减少比率,对移植患者的那不勒斯预后得分进行比较.
- 为了确定那不勒斯预后得分是否预测移植后的早期移植功能.
主要方法:
- 对93名脏移植接受者的回顾性研究 (2020年1月 - 2023年1月).
- 根据术后第二天的肌素降低比率 (>30%对<30%),患者被分为两组.
- 在所有患者的手术前计算的那不勒斯预后得分.
主要成果:
- 两组之间总胆固醇或白蛋白没有显著差异.
- 肌素降低比率<30%的患者患有 3-4 (P=0.032) 的那不勒斯预后得分的患病率更高.
- 多变量分析显示,在那不勒斯预后得分为3-4的患者中,肌素降低<30%的可能性增加了3.151倍 (P=0.019).
结论:
- 手术前的炎症和营养状况,如那不勒斯预后得分所示,可能会影响早期移植功能.
- 高的那不勒斯预后得分与降低的肌素减少比率有关,这表明移植功能障碍的潜在风险.
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