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Updated: Jun 14, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
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在一个新的模型中,追踪从早期前发病到活跃多发性骨髓瘤的细胞免疫反应

Suchita Suryakant Jadhav1, Galia Luboshits1, Bjarne Bogen2

  • 1Department Chemical Engineering & Biotechnology, Ariel University, Ariel, Israel.

European journal of immunology
|October 24, 2023
PubMed
概括

研究人员开发了一种针对多发性骨髓瘤的小鼠模型,在200天内跟踪免疫变化. 这个模型揭示了T细胞疲劳和抑制剂的发展,在多发性骨髓瘤的临床症状之前.

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相关概念视频

Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...