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Updated: Jul 12, 2025

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
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奥普托普罗菲林:应用细胞应激的一个单元生物传感器

Noah Mann1, Jahiem Hill1, Kenneth Wang2

  • 1Department of Chemistry, East Carolina University, Greenville, North Carolina, United States.

bioRxiv : the preprint server for biology
|October 24, 2023
PubMed
概括

研究人员开发了OptoProfilin,一种光学激活的蛋白质,以感知细胞应激. 这种单元生物传感器可以检测细胞骨的变化,为神经退行性疾病研究提供了一个新的工具.

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相关概念视频

Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
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