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Updated: Jul 12, 2025

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通过免疫球蛋白A抑制上皮细胞增殖和瘤发生

Gregory P Donaldson, Gabriella L Reis, Marwa Saad

    bioRxiv : the preprint server for biology
    |October 24, 2023
    PubMed
    概括

    免疫球蛋白A (IgA) 缺乏会通过改变表皮细胞对肠道微生物的反应,增加小鼠结直肠瘤的易感性. 通过DMBT1和Notch信号传递,IgA调节细胞循环,以保持粘膜的健康.

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