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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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E. C. Tolman emphasized the purposiveness of behavior — the idea that much of our behavior is goal-directed. For instance, employees who aim for a promotion work diligently to meet their targets. Tolman argued that when classical conditioning and operant conditioning occur, the organism acquires certain expectations. In classical conditioning, a child might fear a dog because they expect it to bite. In operant conditioning, a person might consistently work overtime because they expect a...
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In operant conditioning, the timing of reinforcement is crucial. For animals like rats and cats, immediate reinforcement (within a few seconds) is much more effective than delayed reinforcement. For example, a food reward for a rat needs to follow within 30 seconds of pressing a bar to be effective. 
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Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
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Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
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概括

大脑使用后感反来将味道与结果联系起来. 这项研究表明,在饭后重新激活杏仁体中神经味道表示,有助于赋予味道学习的功劳.

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科学领域:

  • 神经科学是一个神经科学.
  • 行为生物学 行为生物学
  • 感官科学 感官科学

背景情况:

  • 动物学习食物偏好和厌恶,基于发布刺激性反.
  • 大脑将味道与延迟发送的消化信号联系在一起的机制仍然不清楚.

研究的目的:

  • 调查大脑如何赋予信誉的味道在晚餐期间经历的食物与延迟的帖子刺激反.
  • 识别潜在的味道厌恶学习的神经机制.

主要方法:

  • 在厌恶性后刺激性学习期间,对小鼠的大脑全局激活模式进行了调查.
  • 结合了高密度的杏仁体记录与后脑疾病细胞的光遗传刺激.
  • 检查了新鲜味道与熟悉味道的神经表征.

主要成果:

  • 杏仁体区域的网络在学习过程中被新鲜的味道优先激活.
  • 经过消化不良信号,桃体重新激活了最近一顿饭的新味道表示.
  • 恶心驱动的重新激活加强了神经反应,稳定了味道表现.

结论:

  • 杏仁体味道表示的后消化反应是味道学习中的时间信用分配的关键机制.
  • 这一过程使大脑能够将味道与其延迟的后果联系起来.
  • 了解这种机制可以揭示大脑如何从经验中学习.