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Updated: Jul 12, 2025

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
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VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

Published on: December 28, 2015

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从重链和轻链BCR序列与Dowser配对中推断出B细胞类型

Cole G Jensen1, Jacob A Sumner1,2, Steven H Kleinstein1,3,4

  • 1Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA.

bioRxiv : the preprint server for biology
|October 24, 2023
PubMed
概括

将配对抗体光链纳入遗传树结构可以显著提高准确性和可重复性. 建议采用具有分离基因分区的最大概率方法来进行强大的B细胞分化,特别是在混合数据类型的情况下.

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