在高度采样个体大脑中的结构-功能合
bioRxiv : the preprint server for biology
|October 24, 2023
概括
大脑结构 (SC) 支持大脑功能 (FC). 个体脑部扫描显示,SC在视觉,运动和带膜区域强烈预测FC,挑战了关于大脑组织的先前假设.
科学领域:
- 神经科学是一个神经科学.
- 大脑的连接性 大脑的连接性
- 系统神经科学 系统神经科学
背景情况:
- 结构连接 (SC) 是功能连接 (FC) 的基础,使认知和行为成为可能.
- 以前的研究表明,SC-FC合在整个大脑中有所不同,在单模区域比协会区域更强.
- 集团平均数据对个人特定的SC-FC关系的理解有限.
研究的目的:
- 为了研究个体特定的结构功能连接 (SC-FC) 关系.
- 为了确定单模态-异模态梯度是否完全解释了整个大脑的SC-FC合.
- 探索SC-FC合在更高层次的关联区域,特别是带状回形.
主要方法:
- 在三名健康参与者中获得了密集采样扩散权重MRI (用于SC) 和静止状态fMRI (用于FC).
- 在个人层面分析了SC-FC通信.
- 在不同大脑区域中比较了SC-FC合模式.
主要成果:
- SC在视觉和运动系统中强烈预测了FC,与之前的工作一致.
- 此外,SC还强烈预测了前和后带膜区域的FC.
- 一个简单的单模向异模梯度不能完全捕捉观察到的SC-FC合模式.
结论:
- 个人特异性分析完善了对大脑结构功能关系的理解.
- 带状皮质表现出一种独特的结构-功能合模式,与典型的异模协会区域不同.
- 研究结果强调了个体变异性在绘制大脑网络和理解神经系统疾病方面的重要性.
更多相关视频
08:36Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
Published on: March 21, 2019
7.3K
09:44Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
Published on: March 8, 2024
4.8K
相关概念视频
Functional Brain Systems: Reticular Formation
2.0K
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
2.0K
Organization of the Brain
819
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
819
Functional Brain Systems: Limbic System
2.9K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
2.9K
Brain Imaging
235
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
235
