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Updated: Jul 12, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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ASPSCR1-TFE3通过在六度VCP/p97周围组织增强器循环来重新编程转录

Amir Pozner, Shiv Prakash Verma, Li Li

    bioRxiv : the preprint server for biology
    |October 24, 2023
    PubMed
    概括

    对于ASPSCR1-TFE3蛋白来说,VCP/p97蛋白是必不可少的,它可以驱动罕见的癌症,如膜软部肉瘤 (ASPS) 和Xp11重组细胞癌 (RCC). 抑制VCP/p97为这些具有挑战性的疾病提供了一个有希望的新治疗策略.

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