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Updated: Jul 12, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Published on: May 6, 2019

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在IRF8突变B细胞淋巴瘤中,通过在MHC CII复合体中对抗原处理和呈现的CD74依赖性放松调节来逃避免疫力

Zhijun Qiu, Jihane Khalife, An-Ping Lin

    bioRxiv : the preprint server for biology
    |October 24, 2023
    PubMed
    概括

    在扩散性大B细胞淋巴瘤 (DLBCL) 中IRF8基因的突变会损害免疫监测. 这些IRF8变体通过改变抗原呈现和重塑瘤微环境来促进瘤生长,从而促进免疫逃生.

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