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Updated: Jul 12, 2025

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
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Published on: September 13, 2018

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RAP2 GTPase与细胞骨在Hippo管道调节中的相互作用

Chenzhou Wu1,2, Xiaomin Cai1,2, Ying Wang1,2

  • 1Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

bioRxiv : the preprint server for biology
|October 24, 2023
PubMed
概括

RAP2 GTPase集成细胞骨信号来调节Hippo信号,影响器官大小和癌症. 它的缺失破坏了细胞对机械线索的反应,影响了像LATS1/2.2.这样的关键激酶.

关键词:
河马的信号传递在MAP4K中,您可以使用MAP4K.在 RAP2 GTPase 中使用.细胞骨架 细胞骨架能量压力 能量压力机械传导 机械传导

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