在CAR-T细胞治疗复发/阻断性伯基特淋巴瘤后的骨髓无形成症
Troy J Kenkel1, Nithya Sridhar2, Lindsay R Hammons3
1Department of General Internal Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Medical sciences (Basel, Switzerland)
|October 24, 2023
概括
免疫效应细胞相关的血细胞性淋巴细胞类似综合征 (IEC-HS) 可能发生在CAR-T疗法后,有时会导致骨髓无形成. 这一案例凸显了在CAR-T治疗后对IEC-HS的严重并发症和进一步研究的需要.
科学领域:
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
背景情况:
- 化学抗原受体T细胞 (CAR-T) 疗法是复发/耐药B细胞淋巴瘤的标准治疗方法.
- 免疫效应细胞相关的血细胞性淋巴细胞类似综合征 (IEC-HS) 是CAR-T后新发现的一种并发症.
- 骨髓 (BM) 无形成症,血造原生细胞的严重减少,是IEC-HS的不常见但严重的表现.
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