咳,呼吸和声带功能的恶化在多系统性缩患者
Takashi Asakawa1,2, Mieko Ogino3, Naomi Tominaga3
1Department of Clinical Medical Sciences, Rehabilitation Medicine, Graduate School of Medicine, International University of Health and Welfare, Narita 286-8686, Japan.
Neurology international
|October 24, 2023
概括
在患有多重系统缩 (MSA) 的患者中,行走能力下降与咳功能和呼吸强度的降低有关. 这凸显了移动对于维持MSA患者呼吸系统健康的重要性.
科学领域:
- 神经学 神经学
- 肺部病理学 肺部病理学
- 康复医学 康复医学 康复医学
背景情况:
- 多重系统缩 (MSA) 是一种渐进的神经退行性疾病.
- 咳功能受损和呼吸道肌肉衰弱是MSA患者的重大问题,可能导致诸如肺炎等并发症.
研究的目的:
- 调查MSA患者的门诊状态和咳功能之间的关系.
- 为了评估呼吸功能,呼吸肌肉强度和与MSA中的移动性相关的最大发声时间.
主要方法:
- 评估了17名可能的MSA患者,分为门诊和非门诊组.
- 评估包括咳峰值流量 (PCF),呼吸功能测试,呼吸肌肉强度测量,最大发音时间 (MPT) 和功能尺度 (UMSARS,MDS-UPDRS第三部分).
主要成果:
- 与 ambulatory 患者相比,非 ambulatory MSA 患者的 PCF,呼吸功能,呼吸肌肉强度和 MPT 显著降低.
- 一个显著的比例的非健行患者不能执行空气堆叠.
- 在非健行组中观察到更高的UMSARS和MDS-UPDRS第三部分分数.
结论:
- 在MSA的行走功能障碍与咳和呼吸系统相关功能的下降有关.
- 保持或改善行走能力可能对保持MSA患者的呼吸系统健康至关重要.
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