左心房尾关闭:今天和明天的旅程
Marvin Louis Roy Lu1, David Bowers De Lurgio2
1Adventhealth Daytona Beach, Daytona Beach, Florida.
Current opinion in cardiology
|October 24, 2023
概括
穿皮左心房尾关闭 (LAAC) 装置为无法服用抗凝药的心房患者提供安全有效的中风预防方法. 目前正在进行的研究解决了设备的局限性,如泄漏和血栓.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 预防中风 预防中风
背景情况:
- 心房动 (AF) 显著增加了中风风险.
- 长期抗凝药是标准的中风预防方法,但在一些AF患者中是禁忌的.
- 左心房尾关闭 (LAAC) 作为一种替代疗法而出现.
研究的目的:
- 审查穿皮LAAC器件的发展和理由.
- 检查LAAC设备,技术和风险减轻策略的演变.
- 探索目前对LAAC在AF患者中风预防方面的潜力和局限性的理解.
主要方法:
- 对LAAC设备的临床试验和现实数据的审查.
- 分析设备的演变,植入技术和安全概况.
- 评估周围设备泄漏和血栓形成作为植入后的担忧.
主要成果:
- 多项试验证实了LAAC器件用于预防中风的安全性和有效性.
- 在LAAC后,外周器件泄漏和血栓形成仍然是重大问题.
- 现实世界的数据表明,双重抗血小板治疗可能与LAAC后的短期抗凝药一样有效.
结论:
- 在高风险的AF患者中,LAAC设备是预防中风的可行选择.
- 这些设备在患有抗凝血药物禁忌的患者中提供保护.
- 持续的研究和设备的改进是必要的,以解决植入相关的并发症.
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