在结肠外科手术中进行膀导管管理的多中心,前性,随机对照非劣势试验
Xavier Serra-Aracil1, Jose M Hidalgo1, Arturo Dominguez2
1Coloproctology Unit, General and Digestive Surgery Department, Parc Tauli University Hospital, Institut d'investigació i innovació Parc Tauli I3PT, Universitat Autònoma de Barcelona, Sabadell, Spain.
概括
在腹腔镜结肠手术后立即切除膀导管是安全有效的. 这种方法可以避免急性尿 (AUR),并减少导管相关的并发症,促进早期的患者动员.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术创新 在外科创新.
- 患者的恢复 患者的恢复
背景情况:
- 围绕手术的膀导管实践受到争议,目前的指导方针往往基于开放手术数据.
- 手术后康复 (ERAS) 和快速追踪计划的增强促使人们重新评估导管治疗的持续时间,通常是24-48小时.
研究的目的:
- 为了建立一个理由,缩短膀导管时间在患者接受预定腹腔镜结肠手术.
- 评估手术后立即取出导管的安全性和有效性,以预防急性尿 (AUR).
主要方法:
- 一个多中心,前性,随机控制的非劣势性试验,比较立即取出导管与在手术后24小时取出导管.
- 主要结局:AUR的发生率. 二次结局:尿路感染,住院时间和并发症 (克拉维恩尺度,综合并发症指数).
- 样本大小计算为每组208名患者,假设AUR发病率为11%,非劣势差额为8%.
主要成果:
- 这项研究旨在证明,与24小时取出相比,立即取出导管在预防AUR方面没有劣势.
- 计划对二次结果进行评估,包括尿路感染和整体并发症率.
结论:
- 在腹腔镜结肠手术后立即切除膀导管被提议作为一种安全的替代方案.
- 预计这一策略将降低导管相关的发病率,并促进早期的患者动员.
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