在拔牙后的瘤患者中,对MRONJ风险进行三维临床评估
Catalina Moreno Rabie1,2, Rocharles Cavalcante Fontenele1,2,3, Nicolly Oliveira Santos1,2,3
1OMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium.
Dento maxillo facial radiology
|October 24, 2023
概括
在接受牙拔除的癌症患者中,与药物相关的骨缩 (MRONJ) 是通过放射性迹象预测的,如周骨反应和结节形成. 吸烟和短暂的药物假期也会增加MRONJ的风险.
科学领域:
- 口腔和牙面部外科手术
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 与药物相关的下巴骨髓缩 (MRONJ) 是一种严重的并发症,患者接受治疗抗吸收药物 (ARDs).
- 使用圆束计算机断层扫描 (CBCT) 的术前评估可能有助于识别牙拔除后患有MRONJ风险的患者.
研究的目的:
- 在接受牙切割的瘤患者中确定MRONJ的临床和放射性预测因子.
- 评估与MRONJ发育相关的手术前CBCT发现.
主要方法:
- 这是一项追溯,纵向的病例对照研究,对97名接受牙切割的患者 (47名ARD组,50名对照组) 进行了长期研究.
- 在手术前的CBCT图像被三个盲人检查人员分析,以检查放射特征.
- 统计分析以比较群体之间的MRONJ发展,并确定风险因素.
主要成果:
- 在ARD组中,32%的患者 (38%的部位) 出现了MRONJ.
- 放射学预测因素包括厚厚的牙膜,扩大的牙周带空间,骨质硬化,骨质溶解和结节形成.
- 与多次提取,吸烟和更短的药物假期相关的MRONJ风险增加.
结论:
- 周围骨反应和结节形成可能表明临床前MRONJ.
- 放射性变化在ARD类型之间有所不同 (双酸盐与代诺苏马布).
- 在ARD患者中,CBCT可以揭示预测MRONJ的骨变化.
相关概念视频
Assessment of the Mouth
220
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
220
Tooth Anatomy
507
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
507
Radiological Investigation II: MRI and Ventilation Perfusion Scan
131
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
131
Imaging Studies I: CT and MRI
255
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
255


