在宫缩的怀孕中生殖器神经质的患病率
Maximilian Rauh1, Franziska Werle2, Börge Schmidt3
1University Department of Obstetrics and Gynecology, Clinic St. Hedwig of The Order of St. John, University of Regensburg, Steinmetzstr. 1-3, D-93049, Regensburg, Germany. maximilian.rauh@barmherzige-regensburg.de.
Archives of gynecology and obstetrics
|October 24, 2023
概括
在宫缩短的孕妇中,生殖性Mycoplasma物种的殖民化并没有导致更早的早产. 在这些患者中,抗生素治疗Mycoplasma并没有改变出生时的妊娠年龄.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 在怀孕期间的传染病.
背景情况:
- 妊娠34周前宫缩短是早产的一个危险因素.
- 在孕妇群体中,生殖性Mycoplasma物种的殖民是普遍存在的.
- 在宫缩缩的女性中,生殖性Mycoplasma和早产之间的关联需要进一步调查.
研究的目的:
- 为了调查生殖器Mycoplasma物种的殖民化和早产在宫缩短的孕妇之间的联系.
- 评估抗生素治疗对殖民妇女怀孕结果的影响.
主要方法:
- 在怀孕34周之前对100名怀孕妇女进行了回顾性研究,她们的子宫缩 (≤25毫米).
- 尿液聚合酶连锁反应 (PCR) 检测生殖器菌质菌种 (Ureaplasma spp., Mycoplasma hominis, Mycoplasma genitalium). 尿液聚合酶连锁反应 (PCR) 检测生殖器菌质菌种 (Ureaplasma spp., Mycoplasma hominis, Mycoplasma genitalium). 尿液聚合酶连锁反应 (PCR) 检测生殖器菌种 (Ureaplasma spp., Mycoplasma hominis, Mycoplasma genitalium).
- 对阳性病例的宏类药物治疗;对殖民和非殖民患者之间的结果进行比较,以及治疗与未治疗.
主要成果:
- 37%的患者对Ureaplasma spp.呈阳性,5%对Mycoplasma spp.呈阳性. (所有这些都是与Ureaplasma spp.共同殖民的. ) 的情况.
- 在Mycoplasma阳性和阴性患者之间,出生时妊娠年龄没有显著差异.
- 与阴性患者相比,尿质阳性患者明显年轻;在检查/分娩时的BMI,宫长度或妊娠年龄没有差异.
结论:
- 在宫缩短的女性中,生殖基因菌的殖民化与出生时更早的妊娠年龄没有关联.
- 在这个队列中,抗生素治疗没有改变出生时的妊娠年龄.
- 这些发现质疑在宫缩的产前护理中常规实施Mycoplasma查和抗生素治疗.
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