月经周期相关的变化 巨型后肢运动单元功能
Jessica Piasecki1, Yuxiao Guo2, Eleanor J Jones2
1Musculoskeletal Physiology Research Group, Sport, Health and Performance Enhancement Research Centre, Nottingham Trent University, Nottingham, UK. Jessica.piasecki@ntu.ac.uk.
Sports medicine - open
|October 24, 2023
概括
月经周期阶段没有改变女性的神经肌肉性能. 然而,发动机单元发射率在排卵和中期发育阶段下降,这表明激素对独立于整体表现的发动机单元功能的影响.
科学领域:
- 神经科学是一个神经科学.
- 人体生理学 人体生理学
- 内分泌学 在内分泌学.
背景情况:
- 女性性激素,雌激素和孕,影响神经元功能.
- 月经周期激素波动可能会影响神经肌肉功能,但人类数据有限.
- 之前的研究依赖于动物/细胞模型,缺乏人类运动单元与激素水平的数据.
研究的目的:
- 研究月经周期阶段对人类运动单元功能的影响.
- 量化循环激素和评估整个周期的神经肌肉性能.
- 为了弥合动物模型和人类运动单元对荷尔蒙变化的反应之间的差距.
主要方法:
- 肌肉内电肌图记录了九个女性巨大的横向肌肉中的运动单元潜力.
- 在早期的卵泡,排卵和中期的卵泡阶段收集的数据.
- 分析了神经肌肉性能 (MVC,跳力,稳定,平衡) 和运动单元活动.
主要成果:
- 膝盖延伸器MVC,跳跃力,力稳定性或月经阶段之间的平衡没有显著差异.
- 低值电机单元在排卵和中期发育阶段的发射率降低 (p<0.001).
- 运动单元潜能在排卵和中期发育阶段 (p<0.03) 显示复杂性增加,神经肌肉结位不稳定性没有变化.
结论:
- 神经肌肉的表现在整个eumenorrheic月经周期中保持一致.
- 在高孕激素阶段,低值动力单元发射的减少表明潜在的抑制作用和改变的招聘策略.
- 运动单元功能的收缩强度依赖调节在整个月经周期内发生,而不会影响整体性能.
相关概念视频
01:22Hormonal Regulation of the Menstrual Cycle
408
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
408
01:18Menses Phase
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The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
284
01:19The Menstrual Cycle
860
The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
860
01:19Secretory Phase
779
The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
779
01:20Proliferative Phase
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The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
499
01:30Hormonal Control of the Ovarian Cycle
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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
538