有机气体的毒性相对于典型的过程中排放的颗粒物相比,有机气体的毒性更高
1Department of Environmental Science and Engineering, Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, Fudan University, Shanghai 200433, China.
Environmental science & technology
|October 24, 2023
概括
排放释放有毒有机气体和细颗粒物 (PM2.5). 有机气体比PM2.5具有更高的毒性,强调需要控制排放以减少健康风险.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 化学分析 化学分析
背景情况:
- 排放是城市空气污染的主要来源.
- 过程中排放的细颗粒物 (PM2.5) 和有机气体的特定毒性尚不清楚.
- 评估这些毒性对城市环境中的公共卫生至关重要.
研究的目的:
- 调查和比较PM2.5和排放的有机气体的毒性.
- 为了确定负责这些毒性的关键化学化合物.
- 为控制策略提供信息,以减少与排放相关的健康风险.
主要方法:
- 化学指纹分析排放的化学指纹分析.
- 细胞毒性和反应性氧物种 (ROS) 活性的细胞评估.
- 使用定量结构-属性关系 (QSPR) 进行毒性估计的预测建模.
主要成果:
- 与PM2.5.5相比,有机气体具有显著更高的细胞毒性 (1.9倍) 和ROS活性 (8.3倍).
- 每个质量单位,过程中排放的PM2.5的细胞毒性是上海环境PM2.5的7.1倍,ROS活性是上海环境PM2.5的15.7倍.
- 气态有机物预测的致癌性和呼吸道毒性远远高于有机颗粒物,归因于特定的有机化合物.
结论:
- 过程中排放的有机气体,由于其高毒性和特定化学成分,对健康构成重大风险.
- 像7,9-di-tert-butyl-1-oxaspiro ((4,5) deca-6,9-diene-2,8-dione和2-ethylhexanoic acid这样的化合物是排放毒性的关键因素.
- 针对有机气体的控制措施对于减轻因排放造成的个人暴露风险至关重要.
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