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Updated: Jul 12, 2025

Retroviral CRISPR/Cas9-Mediated Gene Targeting for the Study of Th17 Differentiation in Vitro
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Published on: November 15, 2024

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人类IL-17A蛋白质的产生通过PIP5K1α-依赖的翻译检查点来控制

Shankar K Revu1, Wenjuan Yang2, Dhivyaa Rajasundaram3

  • 1Division of Rheumatology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Science signaling
|October 24, 2023
PubMed
概括

研究人员发现了一种新方法来控制T助手17 (TH17) 细胞中介素-17 (IL-17) 蛋白质的产生. 这种机制涉及调节翻译,而不是转录,为自身免疫性疾病提供潜在的治疗点.

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