跨导管肺SAPIEN 3门植入的结果:一个国际注册表
Sebastien Hascoët1,2,3, James R Bentham4, Luca Giugno5
1Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, Faculté de médecine Paris-Saclay, Université Paris-Saclay, BME laboratory, 133 avenue de la résistance, 92350 Le Plessis Robinson, France.
European heart journal
|October 24, 2023
概括
使用SAPIEN 3的透导管肺植入 (TPVI) 在先天性心脏病 (CHD) 患者中显示出有利的结果. 这项研究研究了右心室外流管 (RVOT) 功能障碍患者的TPVI.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 透气管肺植入 (TPVI) 是对先天性心脏病 (CHD) 中右心室外流通道 (RVOT) 功能障碍的关键治疗方法.
- 有限的数据存在于SAPIEN 3门TPVI的现实世界结果.
研究的目的:
- 为了研究SAPIEN 3门TPVI在患有心脏病的患者中的结果.
- 评估来自EUROPULMS3注册表的患者相关,程序和后续数据.
主要方法:
- 对15个国家的35个中心840名患者的观察数据 (2014-2021) 的回顾性分析.
- 包括患有各种心脏病诊断的患者,包括干缺陷和原生或修补的RVOT.
主要成果:
- 在98.5%的患者中成功植入门.
- 随访时间中位数为20.3个月,感染性内心炎的发病率较低 (3.8%在6年后),肺血栓症的发病率较低 (0.7%在6年后).
- 肺置换发生率在6年后为8.0%,较大的门大小观察到较低的发生率 (P = .009).
结论:
- SAPIEN 3 TPVI在患有心血管疾病的患者中表现出良好的结果,包括那些具有原生或被补丁的RVOT患者.
- 这项研究提供了关于SAPIEN 3门在多样化的CHD群体中的性能的有价值的现实数据.
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