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Updated: Jul 12, 2025

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肠道微生物群和结性脊柱炎之间的因果关系:双向双样本孟德尔随机化分析的见解

Danyan Wang1, Rongqun Li1, Yue Jin1

  • 1School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.

International journal of rheumatic diseases
|October 24, 2023
PubMed
概括

这项研究揭示了肠道细菌和结性脊柱炎 (AS) 之间的因果关系. 准特定的肠道微生物可能为预防和治疗AS提供新的途径.

关键词:
门德尔的随机化结性脊柱炎是一种疾病.自身免疫性疾病是一种自身免疫性疾病.有关因果关系的因果关系我们的肠道微生物群.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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