用扩展的聚四乙烯板进行间隔器安置手术的临床影响,用于粒子治疗
Ryosuke Fujinaka1, Shohei Komatsu2, Kazuki Terashima3
1Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Hyogo, Japan.
Radiation oncology (London, England)
|October 24, 2023
概括
使用扩展聚四乙烯 (ePTFE) 间隔器进行间隔器安置手术,可用于接受颗粒疗法 (PT) 的腹腔骨瘤. 虽然有效,但长期并发症需要仔细监测和干预.
科学领域:
- 在瘤学瘤学.
- 医学物理 医学物理
- 手术瘤学手术瘤学
背景情况:
- 颗粒疗法 (PT) 有利于胃肠道附近的腹膜瘤.
- 扩展聚四乙烯 (ePTFE) 间隔器通过分离器官来增强PT.
研究的目的:
- 评估EPTFE间隔器放置在经过PT的腹腔瘤的安全性,疗效和长期结果.
主要方法:
- 对131名接受ePTFE间隔器安置和PT (2006-2019) 的患者进行了回顾性分析.
- 卡普兰-梅尔方法用于整体存活率 (OS) 和局部控制 (LC) 的计算.
- 根据NCI CTCAE v5.0.0 的复杂度分级.
主要成果:
- 随访时间中位数:36.8个月. 三年工作经验: 60.5%,LC: 76.5%.
- 99.2%的人完成了PT. 3级以上的并发症:急性3.1%,晚期9.9%.
- 10名患者 (7.6%) 需要切除间隔器.
结论:
- 对于PT在腹腔皮层恶性瘤中,ePTFE间距放置在技术上是可行的和可以接受的.
- 发生了严重的晚期并发症,突出显示了不可吸收的间隔器的风险.
- 仔细的长期跟踪和及时干预对于管理ePTFE间隔器并发症至关重要.
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