患有肝硬化的患者中萨尔科佩尼亚的患病率和危险因素:一项观察性研究
Ammara Abdul Majeed1, Hafeezullah Shaikh1, Abdur Rasheed2
1National Institute of Liver and GI Diseases, Dow University Hospital, Karachi, Pakistan.
JPMA. The Journal of the Pakistan Medical Association
|October 25, 2023
概括
肌肉质量的丧失,即缩症,在肝硬化患者中非常普遍. 晚年和肝病的严重程度是关键预测因素,强调了早期检测和干预的必要性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 肝硬化是一种严重的肝脏疾病,与显著的肌肉损耗有关.
- 萨科佩尼亚对健康构成重大风险,影响患者的治疗结果和生活质量.
研究的目的:
- 为了确定患有肝硬化病的患者中的患病率.
- 在这个人群中确定与肉症相关的独立预测因子.
主要方法:
- 一项观察性,横截面研究,涉及386名肝硬化患者 (年龄18-60岁).
- 根据亚洲萨尔科佩尼亚工作组2019年指南 (手握强度,椅子站测试) 进行的萨尔科佩尼亚评估.
- 用SPSS 26收集和分析了临床和实验室数据.
主要成果:
- 在研究的肝硬化患者中,81.3%的患者中检测到肉症.
- 在男性 (59%) 和45岁以上 (84.7%) 的人群中,患病率更高.
- 发现了萨尔科佩尼亚与年龄,椅子运动,手握力,血红蛋白,白蛋白和水平之间的重要关联.
结论:
- 在肝硬化患者中,sarcopenia的发病率很高.
- 随着年龄的增长,并发性疾病和肝脏衰竭是导致肝硬化发生的肉类的危险因素.
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