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Updated: Jul 12, 2025

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
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A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates

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了解酸DNA在SBD蛋白质分子识别中的基础和骨干贡献

Jiayi Li1, Shenggan Luo1, Xingyu Ouyang1

  • 1State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China. yileizhao@sjtu.edu.cn.

Physical chemistry chemical physics : PCCP
|October 25, 2023
PubMed
概括

细菌DNA酸 (PT) 修饰结硫结合蛋白 (SBDs),影响表观遗传学. 研究人员分析了SBD与PT-DNA的相互作用,揭示了核心部位以外的扩展识别,并确定了关键蛋白质残留物.

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