Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Solvents01:12

Solvents

64.7K
A solvent is a substance, most often a liquid, that can dissolve other substances. Here, the substance being dissolved is called a solute. When a solvent and a solute combine, they form a solution - a homogenous mixture of both the solvent and the solute. Water is a universal biological solvent. Its polar structure allows it to dissolve many other polar compounds. The ability of water to dissolve is governed by a balance between water molecules binding to each other and binding to the solute.
A...
64.7K
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry01:20

Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry

209
Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
209
Chemical and Solubility Equilibria02:21

Chemical and Solubility Equilibria

4.1K
The free energy change associated with dissolving a solute in a liter of solvent is called the free energy of a solution, ΔGsolution. The overall ΔGsolution is expressed as the balance of ΔGinteraction against the always-favorable free-energy of mixing, ΔGmixing. Solution formation is favorable if  ΔGsolution is less than zero, whereas it is unfavorable if ΔGsolution is greater than zero. In short, for a solution to form and complete dissolution to take place,...
4.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Revisiting the Immunological Landscape of Locoregional Therapies for Gastrointestinal Cancers: A Shift Toward Interventional Immuno-Oncology.

Current oncology reports·2026
Same author

Correction: Bahloul et al. Investigating the Wound-Healing Potential of a Nanoemulsion-Gel Formulation of <i>Pituranthos tortuosus</i> Essential Oil. <i>Gels</i> 2024, <i>10</i>, 155.

Gels (Basel, Switzerland)·2026
Same author

Toward Safer and Greener Insulation: Formaldehyde-Free, Flame-Retardant, and Bio-Based Phenolic Foams from Tannin and Modified-Lignin Combination.

Materials (Basel, Switzerland)·2026
Same author

Machine Learning for the Prediction of Size and Encapsulation Efficiency of mRNA-Loaded Lipid Nanoparticles Following a Postencapsulation Approach.

ACS applied bio materials·2025
Same author

Seasonal Effect on the Chemical Composition of Mimosa tenuiflora (Willd.) Poir Stem Bark from the Semi-Arid Region of Pernambuco, Brazil.

Chemistry & biodiversity·2025
Same author

Natural deep eutectic solvents (NaDES): green solvents for pharmaceutical applications and beyond.

Green chemistry : an international journal and green chemistry resource : GC·2025

相关实验视频

Updated: Jul 12, 2025

Preparation of Binary and Ternary Deep Eutectic Systems
06:15

Preparation of Binary and Ternary Deep Eutectic Systems

Published on: October 31, 2019

12.0K

深度美容溶剂:一种环保的设计,用于制药工程.

Feras Oyoun1,2, Antoniya Toncheva2, Luis Castillo Henríquez1

  • 1CNRS, Inserm, Chemical and Biological Techniques for Health (UTCBS), Université Paris Cité, School of Pharmacy, 4 avenue de l'Observatoire, F-75006, Paris, France.

ChemSusChem
|October 25, 2023
PubMed
概括

研究人员在药物配方中探索了深层欧性溶剂. 这些溶剂利用键来增强药物输送和治疗应用,为先进的药物开发铺平了道路.

更多相关视频

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

9.9K
Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
06:52

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

Published on: October 30, 2018

35.9K

相关实验视频

Last Updated: Jul 12, 2025

Preparation of Binary and Ternary Deep Eutectic Systems
06:15

Preparation of Binary and Ternary Deep Eutectic Systems

Published on: October 31, 2019

12.0K
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

9.9K
Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
06:52

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

Published on: October 30, 2018

35.9K

科学领域:

  • 材料科学 材料科学 材料科学
  • 化学工程是化学工程的重要组成部分.
  • 制药科学 制药科学

背景情况:

  • 作为各种化学应用的新型介质,深度浸泡溶剂 (DES) 正在引起人们的注意.
  • 结合相互作用在DES的形成和特性中起着至关重要的作用.
  • 制药行业寻求创新的配方策略,以改善药物输送和治疗疗效.

研究的目的:

  • 为了突出深层水溶剂的制备和应用.
  • 强调键受体和键供体相互作用在DES形成中的作用.
  • 展示DES在药物配方和治疗应用中的潜力.

主要方法:

  • 关于深层感溶剂制备的文献综述.
  • 在DES中分析结机制.
  • 在药物配方中探索DES应用.

主要成果:

  • 通过键受体和供体相互作用,可以有效地制备深层性溶剂.
  • 这些溶剂显示出药物配方的巨大潜力.
  • DES为治疗应用提供了有前途的途径.

结论:

  • 深度环氧溶剂是用于制药应用的多功能和可调节的介质.
  • 结合是设计有效的DES药物输送的关键.
  • 对DES的进一步研究有望促进药物配方和治疗的进步.