合成和物理化学特征介质酸和其在牙膏配方中的应用
Azarmidokht Nikfallah1,2, Ali Mohammadi3,2, Mohammadsadegh Ahmadakhondi4,5
1Department of Pharmaceutics, Faculty of Pharmacy, Damghan Branch, Islamic Azad University, Damghan, Iran.
Heliyon
|October 25, 2023
概括
一种新的牙科材料 - - 半孔性酸,有效地为口腔健康提供胸腺醇. 使用这种材料制成的牙膏显示出更好的味道和气味,证明其适用于牙科应用.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料科学 牙科材料科学
- 纳米技术 纳米技术
背景情况:
- 半孔酸 (MHA) 具有很高的孔隙性和表面积,非常适合药物输送.
- 它与牙组织的生物相容性使其成为口腔应用的有希望的材料.
研究的目的:
- 为了合成和描述MHA.
- 为了评估MHA作为提摩尔的载体,一种抗菌剂.
- 评估基于MHA的牙膏配方,以促进口腔健康.
主要方法:
- 通过沉合成的MHA,并使用XRD,FTIR,DLS,FESEM和N2吸附-溶解来进行表征.
- 进行了提摩尔加载和释放研究.
- 对牙膏配方进行体感,pH,稳定性和磨损性测试.
主要成果:
- MHA的表面积和孔积明显高于酸.
- 在MHA和氧酸盐配方之间观察到甲基醇释放谱的显著差异.
- 含甲基醇的MHA牙膏表现出优越的感官特性和可接受的pH,稳定性和磨损性.
结论:
- 半孔酸是口服应用中适合提摩尔输送的载体.
- 基于MHA的牙膏配方提供了增强的感官特征,并且适用于牙科.
- 该研究强调了MHA作为牙膏开发中的磨料材料的潜力.
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