膜膜状细胞癌的生存结果和失败模式
Muhammad Umar Qayyum1,2, Ahmed Ali Keerio1, Muhammad Faisal1
1Department of Surgical Oncology-Head and Neck Surgery, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.
International archives of otorhinolaryngology
|October 25, 2023
概括
晚期阶段,组织学质量差,结节转移是膜膜状细胞癌 (SCC) 长期存活率降低的关键指标. 这些因素显著影响了这种罕见的癌症的结果.
科学领域:
- 在瘤学瘤学.
- 头部和部手术 头部和部手术
- 病理学 病理学 病理学
背景情况:
- 大气泡的状细胞癌 (SCC) 是一个罕见的实体,现有数据有限.
- 膜膜SCC的存活率受到瘤阶段,转移,组织学等级和手术边缘的影响.
研究的目的:
- 评估膜膜SCC中总生存率 (OS) 和无疾病生存率 (DFS).
- 分析边际状况,组织学差异化,患者习惯和转移对生存结果的影响.
主要方法:
- 从2003年到2017年对医院电子数据库的回顾性分析.
- 包括雄大气泡的病学诊断的SCC,不包括相邻的子部位和非治愈意图的病例.
- 评估临床病理学数据以评估生存预测因素.
主要成果:
- 超过一半的患者呈现了第四阶段瘤;大约四分之一的患者患有结节转移.
- 瘤复发与晚期和组织学差异化相关.
- 两年和五年的OS率分别为54.5%和30.3%.
结论:
- 晚期瘤阶段,较高的组织学等级和结节转移的存在被确定为显著的负预后标志物.
- 这些因素对于预测膜膜SCC患者的长期生存至关重要.
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