患者在急性冠状动脉综合征后对他们的心血管药物的信念:一项前性观察研究
Arden R Barry1,2, Erica H Z Wang1,3, Doson Chua1,3
1Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada.
CJC open
|October 25, 2023
概括
患者对急性冠状动脉综合征 (ACS) 后二次预防药物的信念保持稳定,尽管必要性的信念下降. 监测这些信念对于改善坚持和预防复发性心血管事件至关重要.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 健康心理学 心理健康心理学
背景情况:
- 在急性冠状动脉综合征 (ACS) 后,对二次预防性药物治疗的坚持往往很差,增加了心血管事件的复发风险.
- 患者对药物的信念显著预测了故意的不服药.
研究的目的:
- 通过验证的问卷来评估成年患者对ACS后药物的信念和坚持.
- 为了评估药物信仰和从住院到出院后4周的药物坚持的变化.
- 识别与药物信仰变化相关的因素.
主要方法:
- 在加拿大温哥华圣保罗医院进行前性观察研究 (2022年5月至12月).
- 使用了关于药物的信念问卷 (BMQ) 和药物坚持报告尺度 (MARS-5).
- 在住院期间和4周随访期间使用问卷.
主要成果:
- 47名参与者完成了这项研究;平均年龄64岁,83%是男性;大多数人没有非ST段升高ACS.
- 从出院到4周,整体BMQ需要关注差异 (BMQ-NCD) 或MARS-5得分没有显著变化.
- 观察到BMQ特定需求分量表显著下降 (P=0.002).
- 南亚和中东的种族,兼职工作和男性性别与BMQ-NCD有关.
结论:
- 患者通常对后ACS药物持有有利的信念,必要性的信念略有下降.
- 欧洲血统,兼职工作和男性性别与较低的BMQ-NCD有关.
- 人们注意到自我报告的坚持程度很高;建议对药物必要性信念进行持续评估.
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