过早心血管疾病的全球负担,1990-2019年
Hossam Lababidi1, Pedro Rvo Salerno2, Sojin Youn Wass2
1Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
概括
从1990年到2019年,早发性心血管疾病 (pCVD) 死亡人数在全球上升了25%,男性和低收入地区的死亡率更高. 缺血性心脏病和中风是这种日益增长的全球健康负担的主要驱动因素.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 过早心血管疾病 (pCVD) 缺乏标准化的定义,影响全球卫生战略的制定.
- 现有的PCVD文献集中在北美,在全球负担数据中留下了一个空白.
- 了解全球PCVD趋势对于有效的早期检测和预防战略至关重要.
研究的目的:
- 调查早发性心血管疾病 (pCVD) 相关的发病率和死亡率的全球趋势.
- 利用全球疾病负担数据库分析pCVD趋势从1990年到2019年.
- 确定影响pCVD死亡率的主要人口和区域因素.
主要方法:
- 利用了1990-2019年全球疾病负担 (GBD) 数据库.
- 对15-49岁的个人进行了心血管疾病死亡率,死亡率和残疾调整寿命年 (DALYs) 的检查.
- 分析了根据年龄,性别和社会人口指数 (SDI) 的调查结果.
主要成果:
- 全球每年的pCVD死亡人数增加了25% (1990-2019),而死亡率下降了13%.
- 代谢状况被确定为重要的风险因素;缺血性心脏病和中风是导致死亡的主要原因.
- pCVD死亡率显示,高SDI和低SDI地区之间的差异越来越大,在早产年龄组中,性别差异更大.
结论:
- 早发性心血管疾病 (pCVD) 是一个日益严重的全球健康挑战,不成比例地影响男性和低收入地区的人.
- 缺血性心脏病和中风是全球PCVD负担的主要贡献者.
- 解决pCVD需要有针对性的战略,考虑到区域和性别差异.
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