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Updated: Jun 26, 2026

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

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向分子印记聚合物,以光 bis-urea 和 bis-imidazolium 受体响应并捕获光 tyrosine 表位物

Evgeniia Kislenko1, Anıl İncel2, Kornelia Gawlitza1

  • 1Chemical and Optical Sensing Division, Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Str. 11, D-12489 Berlin, Germany. knut.rurack@bam.de.

Journal of materials chemistry. B
|October 25, 2023
PubMed
概括

研究人员开发了光分子印记聚合物 (fMIPs) 来检测化ZAP70,一种癌症生物标志物. 这一进步使得化的敏感检测成为可能,这对于早期癌症诊断和改善患者治疗结果至关重要.

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相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
Tagging and Fusion Proteins01:24

Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...