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揭示SIN1/MAPKAP1在mTOR复合体中的瘤性作用 2 2

Emilien Ezine1,2, Céleste Lebbe1,2,3, Nicolas Dumaz1,3

  • 1INSERM, U976, Team 1, Human Immunology Pathophysiology & Immunotherapy (HIPI), Paris, France.

Clinical and translational medicine
|October 25, 2023
PubMed
概括

在癌症中准PI3K/AKT/mTOR途径是具有挑战性的,因为它会产生不良影响. 这次审查强调了mTORC2的关键组成部分SIN1,作为各种固体瘤的有前途的治疗标.

关键词:
在 AKT AKT 里面.这就是MAPKAP1的意义.在PI3K中,PI3K是指PI3K.这就是SIN1的意义.癌症 癌症 癌症 癌症 癌症在mTOROR中使用mTOR.在 mTORC2 中,mTORC2 是指mTORC2.信号通道的信号通道.有针对性的治疗.

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