[基于T细胞受体的免疫疗法:一篇评论]
Yuan Chen1,2, George F Gao1,2,3, Shuguang Tan2,3
1Collaborative Innovation Centre of Regenerative Medicine and Medical Bioresource Development and Application Co-constructed by the Province and Ministry, Guangxi Medical University, Nanning 530021, Guangxi, China.
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
|October 25, 2023
概括
T细胞受体 (TCRs) 是抗瘤免疫的关键. 基于TCR的新疗法,包括工程T细胞和蛋白质药物,在治疗各种癌症方面显示出重大前景.
科学领域:
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
- 生物技术是生物技术.
背景情况:
- T细胞对于抗瘤免疫反应至关重要.
- 免疫检查点和采用T细胞疗法已经推进了癌症治疗.
- T细胞受体 (TCR) 识别由MHC呈现的瘤抗原,提供高灵敏度.
结论:
- 基于TCR的策略代表了癌症免疫治疗的重大进步.
- 本综述为开发未来基于TCR的免疫疗法提供了洞察力.
- 对TCR的进一步研究有望为创新的癌症治疗提供希望.
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