在中国的Omicron COVID-19浪潮期间的神经并发症:一个队列研究
Lu Lu1,2, Lei Chen1,2, Peiyu Wang1,2
1Department of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
European journal of neurology
|October 25, 2023
概括
神经系统并发症,包括脑炎和脑病变,在COVID-19 Omicron波期间显著增加. 现有的状况恶化,突出了对这些神经问题的有效治疗方法的进一步研究的需要.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 冠状病毒疾病19 (COVID-19) 与各种神经系统并发症有关.
- 2022年Omicron变种的激增为研究这些影响提供了独特的机会.
研究的目的:
- 在2022年Omicron浪潮期间调查COVID-19的神经复杂症.
- 为了比较Omicron波期间的神经病患者的入院情况与前一年.
主要方法:
- 来自三所高等中心的医疗记录的回顾性审查 (2022年12月 - 2023年1月).
- 对新出现或恶化神经症状的COVID-19患者的人口统计和临床数据的分析.
- 与12个月前同一时期的数据进行比较.
主要成果:
- 在790名注册人员中,436人检测出COVID-19阳性.
- 99名患者经历了新发病或恶化的神经疾病.
- 与前一年相比,观察到平均年龄的增加,脑炎/脑病变的发病率和死亡率.
结论:
- 在Omicron浪潮期间,新发的神经疾病,特别是脑炎和脑病变的显著增加发生了.
- 此外,人们还注意到先前存在的神经疾病的恶化,例如发作.
- 进一步的大规模临床试验是必要的,以建立有效的治疗COVID-19相关的神经疾病.
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