患有代谢综合征的患者的男性尿道狭窄
Ahmet Asfuroglu1, Melih Balci2, Burak Koseoglu1
1Department of Urology, Ankara City Hospital, Ankara, Turkey.
Urology research & practice
|October 25, 2023
概括
代谢综合征没有增加手术后尿道狭窄的复发. 然而,代谢综合征患者在手术后有更多的尿路感染,自导管可能会增加狭窄风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢障碍 代谢障碍 代谢障碍
- 纤维性疾病 纤维性疾病
背景情况:
- 尿道狭窄,这种疾病会导致因纤维化而导致尿道流通阻塞,这是一个重大的临床挑战.
- 代谢综合征是一组包括肥胖,高血压和糖尿病在内的疾病,与系统性纤维化有关.
- 代谢综合征对尿道狭窄发展和复发的潜在影响仍然不完全理解.
研究的目的:
- 调查代谢综合征与尿道狭窄的发生之间的关联.
- 评估代谢综合征对直接视觉内尿道切除治疗患者尿道狭窄的复发率的影响.
- 为了确定尿道狭窄复发的危险因素.
主要方法:
- 对132名男性患者进行了回顾性分析,这些患者在2014年至2021年期间接受了直接视觉内泌尿管切除术,以治疗一次性尿道狭窄.
- 评估收缩特征 (位置,长度,类型),手术时间和术后结果,包括复发和导管持续时间.
- 评估代谢综合征与复发以及其他术后并发症之间的相关性.
主要成果:
- 该研究包括132名男性患者;34.1%的患者出现了复发,而27.3%的患者患有代谢综合征.
- 在复发的患者中,术后随访时间显著长 (P=.033).
- 代谢综合征患者的术后泌尿道感染率显着更高 (P=.001),但代谢综合征与复发 (P=.126) 或导管持续时间 (P=.714) 无关.
- 术后干净间歇性自导管的使用在复发患者中较高 (P=.018).
结论:
- 代谢综合征与直接视觉内部尿道切除术后尿道狭窄复发的风险增加无关.
- 患有代谢综合征的患者出现术后尿路感染的发病率较高.
- 术后使用干净的间歇性自导管可能与狭窄性复发的风险增加有关.
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