基于社区乳腺癌登记处检测方法的乳腺癌结局
Debbie Lee Bennett1, Andrea Marie Winter2, Laura Billadello3
1Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. debbie.bennett@wustl.edu.
Breast cancer research and treatment
|October 25, 2023
概括
在瘤登记册中收集检测方法 (MOD) 数据是可行的,并揭示了乳腺癌特征和结果的显著差异. 这些数据对于量化美国机会性查乳房学的影响至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 生物统计学 生物统计学
背景情况:
- 鉴定机会性查性乳房造影在美国的影响是具有挑战性的,因为缺乏检测方法 (MOD) 数据在国家注册.
- 了解癌症的检测方式 (例如,通过查与临床检测) 对于评估查计划的有效性至关重要.
研究的目的:
- 评估在多中心社区瘤注册表中收集MOD数据的可行性.
- 根据其检测方法 (屏幕检测与临床检测) 来比较乳腺癌的临床病理特征和患者结果.
主要方法:
- 一项回顾性研究分析了密苏里州多中心瘤登记 (2004-2018) 中的5351名乳腺癌患者的数据.
- 经过认证的瘤注册机构提取了MOD,临床病理学数据和治疗信息.
- 统计分析包括分类变量Chi-squared测试和数值变量曼-惠特尼-U测试.
主要成果:
- 与临床检测的癌症相比,屏幕检测到的癌症显著较小,更可能是阴性节点,较低等级和较低阶段.
- 查检测到癌症的患者的隆瘤切除率较高,化疗率较低.
- 查检测到的侵袭性乳腺癌患者的整体存活率显着更高 (89%vs74%).
结论:
- 检测方法 (MOD) 可以在瘤注册表中例行收集并与乳腺癌结果联系起来.
- 基于MOD的乳腺癌特征和结果存在显著差异.
- 建议将MOD常规纳入美国瘤登记册,以准确量化机会性查乳房镜的影响.
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