在诊断前和诊断后对年轻和中年初发性结肠直肠癌的直接医疗支出:基于人口的成本评估研究
Ria Garg1,2, Eric C Sayre3, Reka Pataky4
1University of British Columbia, Faculty of Pharmaceutical Sciences, Vancouver, BC, Canada.
概括
年轻发作的结直肠癌 (yCRC) 造成了大量的医疗保健费用,特别是在诊断后. 这项研究量化了与平均年龄发病的结直肠癌 (aCRC) 相比,yCRC的经济负担.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 公共卫生 公共卫生
背景情况:
- 年轻发性结直肠癌 (yCRC) 发病率正在上升,但其经济影响仍未得到充分研究.
- 了解yCRC的财务负担对于资源分配和医疗保健规划至关重要.
研究的目的:
- 估计和比较与年轻发性结直肠癌 (yCRC) 和平均年龄发性结直肠癌 (aCRC) 相关的直接医疗支出.
- 分析 yCRC 和 aCRC 患者的诊断前和诊断后阶段的医疗保健成本.
主要方法:
- 在加拿大不列颠哥伦比亚省利用了链接的行政健康数据库.
- 包括yCRC (<50岁) 和aCRC (≥50岁) 病例的队列,以及没有癌症的对照.
- 医院住院,医疗保健从业人员和诊断前一年和诊断后一年的药物,包括癌症治疗的直接医疗费用.
主要成果:
- 诊断前的支出是可以比较的:yCRC的6,711美元与aCRC的8,056美元相比.
- 在诊断后,yCRC在初始 (50,216美元对37,842美元),持续 (8361美元对5,014美元) 和终身癌症阶段 (86,125美元对61,512美元) 的年度成本显着更高.
- 在yCRC和aCRC之间没有观察到生命期末非癌症阶段成本的显著差异.
结论:
- 年轻发性结肠直肠癌 (yCRC) 带来了巨大的经济负担,超过了诊断后平均年龄发性结肠直肠癌 (aCRC) 的经济负担.
- 这些综合性成本估计为未来关于yCRC的经济评估和政策制定提供了必要的数据.
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