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Updated: Jul 12, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

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核心检测器:一个灵活和高效的程序,用于对进化多样化的基因组的核心基因组对齐

Mario Fruzangohar1, Paula Moolhuijzen2, Nicolette Bakaj1

  • 1The Biometry Hub, School of Agriculture, Food and Wine, University of Adelaide, Urrbrae, South Australia 5064, Australia.

Bioinformatics (Oxford, England)
|October 25, 2023
PubMed
概括

CoreDetector有效地对准了真核生物的核心基因组序列,比现有的工具提高了灵活性和准确性. 这种计算方法对于分析不同物种的序列变异至关重要.

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A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

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An Integrated Approach for Microprotein Identification and Sequence Analysis09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
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