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TMPRSS2是人类冠状病毒HKU1的功能性受体

Nell Saunders1, Ignacio Fernandez2, Cyril Planchais3

  • 1Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France.

Nature
|October 25, 2023
PubMed
概括

跨膜血清蛋白酶2 (TMPRSS2) 作为HKU1冠状病毒的直接受体,促进细胞进入和感染. 这一发现揭示了一种新的病毒结合策略以及普通感冒冠状病毒的潜在治疗点.

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