在癌症中评估基于偏好措施的内容有效性
Adam E J Gibson1, Louise Longworth1, Bryan Bennett2
1Putnam PHMR Ltd, London, England, UK.
概括
基于特定条件的偏好措施 (PBMs) 对癌症患者的相关性比通用PBMs更好. FACT-8D显示出最好的内容有效性,为瘤学测量策略提供了信息.
科学领域:
- 在瘤学瘤学.
- 健康 结果 研究 研究 结果
- 心理测量 心理测量 心理测量
背景情况:
- 基于偏好的措施 (PBM) 对于在癌症护理中评估与健康相关的生活质量 (HRQoL) 是至关重要的.
- 评估通用和特定疾病的PBM的内容有效性对于告知瘤学开发计划和现实世界的应用至关重要.
研究的目的:
- 通过患者的视角来评估通用和特定疾病的PBM的内容有效性.
- 根据基于共识的标准选择健康测量仪器的标准来评估PBM.
主要方法:
- 个人,半结构面试与96名癌症患者在英国和美国.
- 患者完成了3个通用的PBM和2个特定条件的PBM.
- 面试成绩单的专题和内容分析.
主要成果:
- 特定条件的PBM被评为比通用PBM更相关.
- 癌症治疗功能评估八维 (FACT-8D) 显示了相关性最高的内容有效性.
- 在可理解性方面,EQ-5D-5L被评为最高,FACT-8D和生活质量实用核心10维也表现良好.
结论:
- 虽然PBM通常是充足的,但需要进一步开发,特别是对于长期的癌症影响和治疗副作用.
- 未来的工具应该包含常规的健康,治疗影响和心理项目,以进行全面的癌症HRQoL评估.
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