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IDH1突变损害了抗病毒反应,并增强了质瘤中的性病毒疗法

Xueqin Chen1,2, Jun Liu1, Yuqin Li1

  • 1Department of Pharmacology, School of Medicine, Jinan University, 510632, Guangzhou, Guangdong, China.

Nature communications
|October 25, 2023
PubMed
概括

质瘤中的IDH1突变通过增加DNA甲基化来抑制抗病毒干扰素反应. 这一发现揭示了IDH1突变作为型病毒治疗有效性的预测因素.

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