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Updated: Jul 12, 2025

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MED19编码了两种独特的蛋白质异型,通过不同的基因表达程序在低雄激素下赋予前列腺癌生长

Rachel Ruoff1, Hannah Weber1, Ying Wang2,3

  • 1Department of Microbiology, New York University Grossman School of Medicine, New York, NY, 10016, USA.

Scientific reports
|October 25, 2023
PubMed
概括

这两种形式的MED19,是前列腺癌中雄激素受体 (AR) 的关键调节者,具有不同的作用. 正规的MED19促进了早期癌症的生长,而替代的MED19则有助于转移,这表明了独特的治疗点.

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