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Updated: Jul 12, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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具有反向折叠和蛋白质结构预测的结体设计

Patrick Bryant1,2, Arne Elofsson3,4

  • 1Science for Life Laboratory, 172 21, Solna, Sweden.

Communications chemistry
|October 25, 2023
PubMed
概括

我们开发了一种结合Foldseek,ESM-IF1和AlphaFold2 (AF) 的计算方法来设计结合剂. 这个框架准确地预测了结合亲和力,使得新型诊断和治疗药物的发现成为可能.

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