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微流体晶体管用于液体的自动控制
Kaustav A Gopinathan1, Avanish Mishra1,2,3, Baris R Mutlu1,3
1BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.
Nature
|October 25, 2023
概括
研究人员开发了一种微流体晶体管,类似于电子晶体管,能够精确控制芯片上的流体和粒子. 这种创新允许复杂的流体电路, 推进无电子芯片的实验室技术.
科学领域:
- 流体动力学
- 微流体学
- 电子电路类比
背景情况:
- 微流体学已经推进了分子生物学,诊断和组织工程.
- 需要精确,可扩展的流体操纵,类似于电子电路.
- 之前的微流体晶体管模拟器缺乏关键的晶体管行为,如比例放大.
研究的目的:
- 开发一个微流体晶体管模拟器,复制电子晶体管的功能,包括比例放大.
- 将电子电路设计转化为流体领域.
- 创建先进的微流体控制器和粒子操纵系统.
主要方法:
- 使用流量限制的现象来创建微流体元素.
- 开发了类似于电子元件的微流体电路 (放大器,逻辑门,锁).
- 整合这些组件构建复杂的流体控制器和粒子分配器.
主要成果:
- 创建了一个微流体晶体管,其流压特性类似于电子晶体管的电流电压特性.
- 成功将基本电子电路转化为功能流体电路.
- 展示了一种能够感知,处理和控制个体粒子运动的粒子分配器.
结论:
- 微流体晶体管为微流体芯片上的自动流体控制提供了一个强大的平台.
- 这种方法可以设计复杂的流体电路用于芯片实验室.
- 这项技术提供了无电子操作的液体和单个粒子,进步自主系统.
相关概念视频
01:27Steady Flow of a Fluid Stream
Consider a control volume, such as a pipe with solid boundaries, through which fluid flows and changes direction due to the impulse exerted by the resulting force from the pipe walls. In steady flow, the mass of fluid entering the control volume at a given time, t, with velocity v1, is equal to the mass leaving after infinitesimal time dt, with velocity v2.
During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...
During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...
01:16Control Volume and System Representations
Two key frameworks are employed to analyze mass, energy, and momentum transfer: the control volume approach and the system approach. These frameworks offer different perspectives, depending on whether the focus is on a specific region in space (control volume approach) or a defined mass of fluid (system approach).
The control volume approach considers a stationary region in space through which fluid flows. This region is bounded by a control surface. For instance, in the case of water flowing...
The control volume approach considers a stationary region in space through which fluid flows. This region is bounded by a control surface. For instance, in the case of water flowing...
01:16Conservation of Mass in Finite Cotrol Volume
The principle of conservation of mass is a fundamental law in fluid mechanics and is applied using the continuity equation. We apply the concept to a finite control volume to derive the continuity equation.
A system is defined as a collection of unchanging contents, and the conservation of mass states that a system's mass is constant.
A system is defined as a collection of unchanging contents, and the conservation of mass states that a system's mass is constant.